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Did you know ..?

How our organs work?

The liver & metabolic exchanges

The liver is a vital, multi-functioning organ, governing a majority of detoxification processes and metabolic exchanges. Moreover, the liver is also a gland with exocrine and endocrine characteristics, and as such, it is also responsible for, and participates in many other actions.

Major synthesis,

Processing of nutrients, subsequent break down, and absorption from blood occur in hepatocytes.

 

Others : Metabolic transformations of carbohydrates, as well as lipids; ammonia detoxification; break down of cholesterol cells, cleansing functions; hormonal production – maintenance - & de-activating, re-generation and blood cells supply &; plasma proteins synthesis.

Common Bile ducts

Hepatocytes, the chief functional cells of the liver, will produce bile which is stored in your gallbladder until we eat.  Your gallbladder stores bile, then upon eating it is discharged into your duodenum, and intestines. Bile – a composition of water, bile salts, cholesterol, lipids, acids and auxiliary bilirubin – is being released into bile capillaries, which in turn carry bile, leading into Canals of Hering, and other ducts.  Bile duct is dark green, like the gallbladder; bile is a darkish green, bitter-tasting fluid.  It is an essential component in intestines determining the break-down of fat cells.

Liver diseases

The liver is the only organ in the body that can re-generate itself.  It is possible thus, that the liver will heal itself without any major consequences, having been exposed to a traumatic initiative: however, an aberrant attempt to re-generate the organ can lead to bile ducts alterations, i.e. hyperplasia.  As a result of long-term, chronic damage, there is the subsequent growth of scar tissues, i.e. fibrosis; Liver fibrosis is usually the result of cirrhosis.  Alternatively, an overall & irreversible transformation of liver tissues takes place, whereby scar tissues slowly replace normal functioning liver tissues, i.e. cirrhosis of the liver – when the structural make up of the organ is forever replaced by hard, connective tissues.

Liver failure

Liver failure is a condition of the organ, when it is no longer able to perform its normal functions – the consequences of this either acute or chronic state are dire, indeed.  Other essential body functions start to shut down rapidly.  Liver failure can be described as the most severe degree of liver insufficiency.

 

Liver failure results in a state of biological homeostasis of the body and a metabolic collapse, further leading to a blood-clot formation disorders, build up of fluids in internal cavities, together with kidney failure and brain disorders as well.  In the final stages, a total liver collapse leads to death.  An acute liver failure can occur as a result of a number of health conditions, e.g. an acute, and severe infection / inflammation of liver, which can onset an acute liver steatosis, or a massive tumor growth in the liver tissue, which happens to destroy the main mass of the liver tissue.

Consequences

Liver failure consequences mirror the many functions the liver cease to perform.  Needless to say, that there is a direct connection to other internal organs, namely kidneys, which subsequently are associated with this scenario.  Liver’s metabolic functions are at the centre of the metabolic exchanges of carbohydrates, lipids and amino-acids.

 

Thus, liver failure can be related to a diagnosis of hypoglycemia, in addition the cholesterol levels are likely to rise when bile secretion is not present.  The balance of various amino acids is disturbed, or damaged.  When the cleansing function of liver is affected, there are also changes in the urinary-synthesis cycle identifiable, consequently urea processing, and levels are not altered, and toxic amino acids become detectable in the blood stream.